Heparin induced thrombosis. May complicate renal replacement treatment.

Management of Heparin-Induced Thrombocytopenia During Renal Replacement Therapy.

Awareness is increasing concerning the development of antibodies to heparin-platelet factor 4 complex in both regular hemodialysis patients and those treated with continuous forms of renal replacement therapy. Although the development of antibodies does not result in thrombocytopenia or thrombosis in some patients, most patients present with thrombocytopenia, premature platelet activation, and ...

Heparin‐Induced Hyperkalemia in a Dog Receiving Continuous Renal Replacement Treatment

An 11-year-old, male castrated Australian shepherd dog presented for evaluation of acute exacerbation of chronic kidney disease (CKD). The dog had a history of stage III CKD (borderline proteinuric, blood pressure unknown) that had been stable for 4 years. The dog had last been evaluated 5 months earlier. At that time, blood urea nitrogen (BUN) concentration was 57 mg/dL, serum creatinine (SCr)...

Bilateral Renal Artery Thrombosis due to Heparin-Induced Thrombocytopenia-Thrombosis Syndrome. Successful treatment with longterm application of lepirudin

Heparin induced thrombocytopenia thrombosis (HIT/T) syndrome: diagnosis and treatment.

Heparin induced thrombocytopenia thrombosis (HIT/T) is associated with a high morbidity and mortality. Diagnosis is essentially clinical and negative results of laboratory assays do not exclude the diagnosis. Treatment involves stopping all heparin immediately and giving an alternative thrombin inhibitor. The adoption of low molecular weight heparins is one reason for the reduced incidence of t...

Plasmapheresis in heparin-induced thrombocytopenia and thrombosis.

To the Editor: Thrombosis associated with severe thrombocytopenia is an infrequent, but life-threatening side effect of heparin therapy, which can involve any venous or arterial territory including the cerebral circulation. The treatment of this serious complication has not been satisfactorily resolved. Recently, Becker and Miller reviewed heparin-induced thrombocytopenia with thromboembolism a...